Fatal Fungal Lung infection affects TB recovered patients due to misdiagnosis; experts call for steps to be taken

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The Global Action For Fungal Infections (GAFFI) is calling for improved diagnostic capability for chronic pulmonary aspergillosis (CPA) – especially Aspergillus antibody detection, as well as antifungal therapy. The call is in response to published studies in India and Vietnam that found over the last 12 months1,2 over 50% of patients cured of TB but… Read more »

GAFFI’s David Denning featured in The Conversation, raising awareness of fungal disease and its impact on Aids-related deaths around the world

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  GAFFI’s Chief Executive, Professor David Denning, recently authored an article in the research and analysis publication, The Conversation focusing on the devastating effect fungal disease has on those with Aids. See the article here   Professor David Denning said: “As more and more people are treated for HIV infection, deaths will continue to come… Read more »

Diagnosis of aspergillosis now routine with good performance – if tests are requested

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On World Aspergillosis Day, GAFFI highlights the significant strides forward in the diagnosis of all forms of aspergillosis over the last few years. Major advances include: Introduction of lateral flow assays for Aspergillus antigen Introduction of lateral flow assay for Aspergillus antibody Determination of cut-offs for Aspergillus antibody for multiple tests and countries The increased… Read more »

Should African histoplasmosis be included as a skin Neglected Tropical Disease? Fungal experts think so.

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January 30th is Global Neglected Tropical Diseases (NTD) Day. This is a worldwide campaign to raise awareness of these often-overlooked conditions. World NTD Day serves as a call to action to secure increased resources for neglected tropical diseases, and crucially facilitate political leadership and ownership of NTD programs from affected countries. The 2021 Neglected Tropic… Read more »

Histoplasmosis in PLHIV – the more you look, the more you find in endemic areas

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Exposure to Histoplasma in the air is common in Guatemala (as in many other countries). In ASI ‘s* diagnostic program in collaboration with GAFFI, more and more patients tested positive for disseminated histoplasmosis as more samples were sent.  Narda Medina and colleagues report that in 2017, 1836 people with HIV infection were screened and 120 (6.5%)… Read more »

Indonesian study reveals missed diagnosis of fungal infections in treated TB patients, with global implications

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A study of tuberculosis patients in six Jakarta hospitals has revealed up to 13% of them had fungal lung infection  – or aspergillosis – at the end of their treatment. The findings could, warn the research team from Universitas Indonesia and The University of Manchester, have implications globally wherever TB is found. The study tracked… Read more »

Less than 15% of African countries have access to life-saving diagnostic for common AIDS-defining respiratory illnesses.

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On World AIDS Day, experts call for global commitment towards the purchasing of diagnostic tests for Pneumocystis pneumonia (PCP), a respiratory fungal infection responsible for a high proportion of deaths among HIV positive children and adults in Africa. A recent survey conducted by GAFFI assessing the availability of WHO listed essential diagnostics for fungal diseases… Read more »

Fungal Disease Experts Call for Talaromycosis to be listed as a Neglected Tropical Disease

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An international panel of experts is calling on global health organisations like the WHO to classify Talaromycosis as a Neglected Tropical Disease (NTD). Shanti Narayanasamy, working with Thuy Le at the Duke University School of Medicine, has summarised the strong arguments in favour of NTD designation in a paper in Lancet Global Health, found here… Read more »

Antifungal echinocandins added to the WHO’s Essential Medicines List

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Echinocandin antifungal drugs are the ‘workhorses’ of antifungal therapy in hospitals. The WHO has endorsed their importance by adding them to the 2021 Essential Medicines List for low and middle countries, for both adults and children.    Initially launched in 2002 in Japan and USA, micafungin (Astellas) and caspofungin (Merck) were the first to market… Read more »

GAFFI IS NOW LOOKING FOR NEW BOARD MEMBERS

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GAFFI is committed to strengthening our board based on equality, diversity and inclusion of members with background from our geographical focus areas. We would appreciate, in our first step, to receive applications from female applicants with cultural background from outside Europe. Today we have a strong medical (fungal) expertise, management, marketing and HR are other… Read more »